Gilles de la Tourette syndrome treated effectively with clozapine.
نویسنده
چکیده
A report of Gilles de la Tourette syndrome in a 16-year-old male and a 20-year-old female from the Kingdom of Saudi Arabia, illustrating difficulties in diagnosis, comorbidity and management. A successful trial of clozapine therapy after failure of conventional treatments is reported over a period of more than 2 years and discussed.
منابع مشابه
Clozapine-induced palilalia?.
INTRODUCTION Palilalia is an acquired speech disorder characterised by involuntary and spontaneous repetition of words or phrases two or more times in a row. It can occur in a variety of disorders including postencephalic parkinsonism, pseudobulbar palsy, schizophrenia, Gilles de la Tourette syndrome and others. CLINICAL CASE We describe a case of a 28-year-old man with refractory schizophren...
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Although tics are considered the hallmark of Tourette syndrome, arguably tics may not be the only or primary presenting symptom. For many children diagnosed with Tourette syndrome irritability, frustration intolerance, hyperactivity, inattention, ritual behavior or other difficulties may have been present a number of years before the appearance of tics. Children with Tourette syndrome are often...
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Investigators from Centre de Reference National Maladie Rare 'Syndrome Gilles de la Tourette' and Sorbonne University report white matter abnormalities in the pathways connecting the cerebral cortex, basal ganglia, and thalamus in a group of 49 adults with Tourette syndrome (TS).
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Three deflections or waves of the Contingent Negative Variation (CNV): the Slow Negative Wave (SNW), the Terminal CNV (TCNV) and the Post Imperative Negative Variation (PINV) were studied in 18 adults with Gilles de la Tourette syndrome and in 15 controls. The patients showed a reduced SNW, a normal TCNV and an increased PINV. Moreover, at the right parietal region the patients demonstrated a d...
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ورودعنوان ژورنال:
- Neurosciences
دوره 9 2 شماره
صفحات -
تاریخ انتشار 2003